|
The Gangliosidosis GM1 and GM2 are two different Gen-diseases, they long years ago unnoticed remained in the breeding with Korat-Cats.
The disease symptoms appeared the last time in Southern Europe in 1996.
They belong to a group of diseases, known as lysosomal storage diseases (Fat-storage-diseases)
This Gene Defects come into being only, if both of the parents are carrier.
Both types of Gangliosidosis cause progressive brain disease, but become evoke through different causes. A DNA-Test analyzes
each type of GM independently.
GM1
The neurological signs of Gangliosidose GM 1 by cats appear approximately in the age of 3-6 months.
GM2
The signs of Gangliosidose GM2 starts ealier , 2 months of age, and progress more faster.
GM1 is to be attributable of the deficiency of the enzyme ßgalactosidase and GM2 of the deficiency of the enzyme ßhexosaminidase.
The symptoms of both disease are: Headtremors at the beginning, unable to move their legs until to the paralysis.
Prof. Dr. Henry Baker has created the possibility for a DNA-Test, to identify all Koratcats in the World as carriers and non-carriers.
How does the test start?
Go with your cat to your own Vet. and spent 1 ml. blood and send it well-packed to Prof. Baker/USA.
We sent for prior agreement per TNT over night.
The test is free of charge. The adress is:
Dr. Henry J. Baker Professor and Director Scott-Ritchey Research Center Auburn University Auburn, AL 36849 e-mail: bakerhj@vetmed.auburn.edu
fax:001 334-844-5951
|